After studying the antibacterial, antioxidant, and healing properties of mango, researcher Lesslie Espinosa, from the National Polytechnic Institute (IPN), has developed an extract from mango peel that could accelerate the healing process of superficial wounds.
The research was conducted by Espinoza, who is a doctoral student at the National School of Biological Sciences (ENCB), with the help of researchers Leticia Garduño Siciliano of the ENCB and Marco Aurelio Rodriguez Monroy of the Iztacala Faculty of Higher Studies (FES) of Mexico's National Autonomous University (UNAM).
Both Leticia and Marco helped Lesslie elucidate the phenolic compounds and properties of mango peel from the Ataulfo variety. "We subjected it to a maceration process with a high polarity solvent to extract the phenolic compounds and then we carried out various filtration processes to obtain the crude extract," stated Lesslie Espinosa.
After obtaining the extract, the researchers evaluated its in vitro effectiveness and tested the microbial, antifungal, antibacterial, and antioxidant activity that will help in the healing process, which can sometimes be affected by various factors.
"The remodeling of the wound is naturally carried out in 14 to 30 days but, in the animal model, we verified that at the microscopic level the wound was already closed by day 8 or 9; and that the first two layers of skin had already closed by day 11,” Espinosa detailed.
The next step, according to Espinosa, will be to carry out tests to determine the level of toxicity that the extract could have, despite the fact that the animal test did not show any related effect.