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Obese mothers often pass dietary impacts to offspring

Powerful antioxidant can possibly halt or prevent fatty liver disease

As obesity continues to rise in the U.S., non-alcoholic fatty liver disease (NAFLD) has become a major public health issue, increasingly leading to cancer and liver transplants. Now, new research from the University of Colorado Anschutz Medical Campus has discovered that a powerful antioxidant found in kiwi fruit, parsley, celery and papaya known as pyrroloquinoline quinone -or PQQ- can halt or prevent the progression of fatty liver disease. It was tested on the offspring of mice fed a high-fat Western-style diet.

Growing evidence suggests that childhood obesity and fatty liver disease is influenced by maternal diet and the infant’s microbiome, the community of microorganisms inhabiting the body.

Obesity, which often stems from a high-fat, high-cholesterol, sugary diet, is a major cause of NAFLD. According to the Journal of the American Medical Association, nearly 60 percent of American women of childbearing age are overweight or obese. Numerous studies suggest their children tend to have increased liver fat and a higher risk of becoming obese.

The researchers found that they could halt and prevent liver disease from developing in young mice by feeding their mothers PQQ, the antioxidant found in kiwi fruit, parsley, celery and papaya.

Of course, the cuanschutztoday.org article noted that more work is required to determine if these studies might apply to humans.


Publication date: 1/23/2018


 


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