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Eating grapes can ward off depression, according to study

Including grapes in your diet may have a positive impact on your mental health. Researchers have found that certain grape-derived compounds might be developed for the treatment of depression. The results, published online in the journal Nature Communications, indicate that these natural compounds may reduce depression by targeting newly discovered underlying mechanisms of the disease.

The lead researcher in this study is Giulio Maria Pasinetti, professor at Icahn School of Medicine at Mount Sinai in New York. "The discovery of these new, natural grape-derived polyphenol compounds targeting cellular and molecular pathways associated with inflammation may provide an effective way to treat a subset of people with depression and anxiety.”

Depression is associated with a multitude of pathological processes, including inflammation of the peripheral immune system, a set of biological structures and processes in the lymph nodes and other tissues that protect against disease and abnormalities involving synapses.

However, currently available antidepressants are largely restricted to targeting the systems that regulate serotonin, dopamine, and other related neurotransmitters, and these treatments do not specifically address inflammation and synaptic problems.

India Today reports on previous research that has found that grape-derived polyphenols have some efficacy in modulating aspects of depression, yet the mechanisms of action had largely remained unknown until now.


Publication date: 2/6/2018


 


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